Faculty member
Prof. Dr Julia Sacher
Research Interests
My research centers on the intersection of brain, behavior, and hormones, exploring how neuroendocrine systems dynamically shape cognition and mental health. Hormones work in synergy, not isolation—and our work reflects this principle. Using advanced multimodal neuroimaging (7T MRI, neuroreceptor PET) and large-scale biobank analyses, we investigate how hormonal transitions across the lifespan—from the menstrual cycle to postpartum and perimenopause—influence memory, emotion regulation, stress response, and well-being. We integrate perspectives from neuroscience, endocrinology, and psychology to advance sex- and hormone-informed neuroscience, addressing critical gaps in brain research where women’s health has historically been underrepresented. By combining dense-sampling and high-resolution imaging with inclusive, transparent AI approaches, we aim to capture the fine-grained biological variability that drives individual resilience and vulnerability. Our discoveries have highlighted how natural hormonal fluctuations reshape brain networks, neurochemistry, and even heart–brain coupling, with implications for mood, stress regulation, and long-term health. Through this work, we aim to bridge fundamental gaps in women’s brain health research, generating insights that inform prevention and treatment across the lifespan. Collaboration is at the heart of our work, enabling integrative, team-based approaches to complex questions in brain health.
Available PhD projects
Potential PhD projects can be discussed and would build on ongoing work within our core research areas. Opportunities depend on available funding and fit with the group’s research programme.